PREZCOBIX® Pharmacokinetics
PREZCOBIX® Provides Therapeutic Drug Levels at 24 Hours Post Dose1-3
PREZCOBIX® maintains plasma concentrations 37 times greater than EC50 at 24 hours*1,2
The clinical implications of these data have not been established.
*Based on overall population PK sampling (n=298).
†A PK substudy was conducted in a subset of patients (n=60; 57 TN, 3 TE) enrolled in Safety Study 130. Intensive PK sampling was performed at a study visit occurring between Weeks 2 and 8.
EC50=half maximal effective concentration; OBR=optimized background regimen; PK=pharmacokinetic; SD=standard deviation; TE=treatment-experienced; TN=treatment-naïve.
References: 1. PREZCOBIX® [Prescribing Information]. Titusville, NJ: Janssen Therapeutics, Division of Janssen Products, LP. 2. Data on file. Janssen Therapeutics, Division of Janssen Products, LP. 3. PREZISTA® [Prescribing Information]. Titusville, NJ: Janssen Therapeutics, Division of Janssen Productions, LP.