Skip to content

Dosing

Once-Daily PREZCOBIX® Helps Reduce Pill Burden

Coformulated in a fixed-dose combination1

Pill image 01

  • The recommended dose of PREZCOBIX® is one tablet taken once daily with food as part of combination ARV therapy for HIV-1–infected adults with no DRV RAMs*1

​*DRV RAMs=darunavir resistance-associated mutations: V11I, V32I, L33F, I47V, I50V, I54L, I54M, T74P, L76V, I84V, and L89V.

No drug interaction trials have been performed with PREZCOBIX® or with darunavir coadministered with cobicistat as single entities. Drug interaction trials have been conducted with darunavir coadministered with ritonavir and with cobicistat alone.

No clinically relevant drug-drug interaction is expected when PREZCOBIX® is coadministered.

ARV=antiretroviral; INSTI=integrase strand transfer inhibitor; NNRTI=non-nucleoside reverse transcriptase inhibitor; NRTI=nucleoside reverse transcriptase inhibitor; PDE-5=phosphodiesterase type 5; PI=protease inhibitor; PK=pharmacokinetic.

Reference: 1. PREZCOBIX® [Prescribing Information]. Titusville, NJ: Janssen Therapeutics, Division of Janssen Products, LP.